Chloroquine Phosphate Tablets

• Product Name : Chloroquine Phosphate Tablets
• Trade Name : As per customer request
• Available Strength : 100 mg, 250 mg, 500 mg
• Available Combination : Chloroquine Phosphate+ Primaquine Tablet
• Packing : 10X10 tablet/box
• Pack Insert/Leaflet : Yes
• Therapeutic use : Antimalarial
• Production Capacity : 10 million tablet/month

Product Details:

What is Chloroquine Phosphate Tablets?
Chloroquine phosphate is a 4-aminoquinoline compound for oral organization. It is a white, odourless, unpleasant-tasting, crystalline substance, openly dissolvable in water. Chloroquine phosphate tablets are used as an antimalarial and amebicidal drug.
Detailed information related to Chloroquine Phosphate Tablets’s uses, composition, dosage, side effects and reviews is listed below.

Chloroquine Phosphate Tablets Uses
Chloroquine Phosphate Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

• Chloroquine phosphate tablets are demonstrated for the: Treatment of uncomplicated malaria because of susceptible strains of P. falciparum, P.malariae, and P.vivax. It is profoundly successful as a suppressive agent in patients with P.vivax or P.malariae, ending of acute attacks, and essentially extending the interval between treatment and relapse.
• Chloroquine Phosphate Tablet is used for the Treatment of extra intestinal amebiasis.

Chloroquine Phosphate Tablets Working, Mechanism of Action and Pharmacology
Chloroquine Phosphate Tablets improves the patient’s condition by performing the following functions:

• Chloroquine Phosphate Tablet is a 4-aminoquinoline, is an anti-protozoal agent. Chloroquine, may apply its impact against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme.
• It can likewise repress certain enzymes by its association with DNA.
• Action in Vitro and in Clinical Infections: Chloroquine is dynamic against the erythrocytic types of susceptible strains of Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax.
• Chloroquine isn’t dynamic against the gametocytes and the exoerythrocytic structures including the hypnozoite stage (P. vivax and P. ovale) of the Plasmodium parasites.
• In vitro investigations with Chloroquine exhibited that it is dynamic against the trophozoites of Endamoeba histolytica.

Chloroquine Phosphate Tablet – Composition and Active Ingredients
Chloroquine Phosphate Tablet is composed of the following active ingredients (salts)
Available Combination:

• Chloroquine Phosphate+ Primaquine Tablet

The active ingredient is Chloroquine Phosphate.

• Each tablet also contains the inactive ingredients Lactose, Starch, Sodium Starch Glycol late, Magnesium Stearate and Stearic Acid.

Please note that this medicine may be available in various strengths for each active ingredient listed above.

Chloroquine Phosphate Tablet – Side-effects
The following is a list of possible side effects that may occur from all constituting ingredients of Chloroquine Phosphate Tablet. This is not a comprehensive list. These side effects are possible, but do not always occur. Some of the side effects may be rare but serious. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

• Adverse effects are rare at normal dosages and are usually reversible.
• They include:disturbances, nausea, vomiting, diarrhoea and abdominal cramps.
• Skin disorders including urticarial, skin discolouration.
• Muscular damage.
• Low blood pressure or changes in heart rate.
• Hearing disorders, such as reduced hearing or tinnitus.
• Effects on the central nervous system such as convulsions, psychotic reactions.
• Including hallucinations (rarely), anxiety and personality changes.

Chloroquine Phosphate Tablets – Precautions & How to Use
Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Precautions:-

• • You are allergic to Chloroquine Phosphate or any of the other ingredients in the tablet.
  • You are pregnant or planning to be. You should consult your doctor before taking these tablets if:
  • You suffer from Porphyria.
  • You suffer from kidney disorders.
  • You suffer from liver disorders, particularly cirrhosis.
  • You suffer from Psoriasis.
  • You suffer from convulsions or other nervous disorders.
  • suffer from gastro-intestinal disorders.

Chloroquine can cause the bringing down of the blood glucose level. Please contact your doctor. This medicine contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, before taking this medicine take advice by your doctor.

How to Use:-

• For adults, the elderly and children over 12 years old, the usual dose is:2 tablets as a single weekly dose. The dose should be started 1-2 weeks before entering an endemic area.
• The product should only be given to children younger than 12 years old under the supervision of a doctor.
• The product should only be used to treat malaria under medical supervision.